Abnormal subendocardial function in restrictive left ventricular disease.

Abnormal subendocardial function in restrictive left ventricular disease.

OBJECTIVE To study possible disturbances in left ventricular long axis function in patients with a restrictive filling pattern. DESIGN Prospective examination of the left ventricular transverse and longitudinal axes, transmitral flow, and the apexcardiogram. SETTING A tertiary referral centre for cardiac diseases. SUBJECTS 21 normal subjects, age (SD) 51(11); 30 patients of similar age wi...

Left Ventricular Subendocardial Ischemia

Severe valvar aortic stenosis (VAS) and supravalvar aortic stenosis (SVAS) each may cause left ventricular (LV) subendocardial ischemia and infarction, even with patent coronary arteries. LV ischemia in VAS has been related to reduced coronary perfusion relative to raised metabolic requirements, whereas this mechanism of ischemia has not been widely accepted in SVAS because coronary perfusion p...

Abnormal Left Ventricular Contraction

Twenty-five patients with pure mitral stenosis and nine normal subjects were studied by selective left ventricular cineangiocardiography. Left ventricular volumes were measured at end systole, throughout diastole, and at end diastole. Although filling curves showed that the left ventricles filled slowly in patients with mitral stenosis, normal end-diastolic volumes were attained provided diasto...

Left ventricular function in coronary artery disease.

Subendocardial Fibrosis in Left Ventricular Hypertrabeculation-Cause or Consequence?

Left ventricular noncompaction has been classified as a primary cardiomyopathy with a genetic origin. This condition is morphologically characterized by a thickened, two-layered myocardium with numerous prominent trabeculations and deep, intertrabecular recesses. Recently, it has become clear that these pathological characteristics extend across a continuum with left ventricular hypertrabeculat...